Desired Over Have (D/H × V): The Basic Dosage Formula

Shows the work. Every example is computed with the formula and numbered steps. For study and exam practice, not for patient care.

Desired over Have: The formula method: amount to give = Desired (ordered dose) ÷ Have (dose on hand) × Vehicle (the form or volume the dose on hand comes in).

Desired over Have (D/H × V, sometimes D/H × Q for quantity) is the most common dosage formula:

  • D, Desired: the dose ordered.
  • H, Have: the dose on hand, from the label.
  • V, Vehicle: what that dose comes in, 1 for a tablet or capsule, or the mL on the label for a liquid.

Amount to give = D ÷ H × V. D and H must be in the same unit, so convert first (g to mg, mg to mcg) when they differ.

It is one of three methods taught for the same problems; ratio and proportion and dimensional analysis reach the same answer.

Worked exampleIM injection

Order: promethazine 30 mg IM. Available: promethazine 50 mg/mL.

Desired dose
30 mg
Have
50 mg
Vehicle
1 mL
Give as
mL (liquid or injection)

Formula Amount = desired ÷ have × vehicle.

  1. mL = desired dose ÷ concentration.
  2. 30 mg ÷ 50 mg/mL = 0.6 mL.
  3. 0.6 mL is exact, so no rounding is needed.

Answer 0.6 mL

All glossary terms

Sources

  1. Clinical Calculations: With Applications to General and Specialty Areas — Elsevier (Kee, Marshall, et al.)
  2. Calculate with Confidence — Elsevier (Morris)

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